Manager/Senior Manager – Compound Management

About Us: Entact Bio is a preclinical stage biotechnology company developing a new class of drugs that enhance the function of beneficial proteins. Launched by a founding team deeply rooted in deubiquitinase (DUB) biochemistry, chemical biology, disease biology, and small-molecule drug development, Entact has designed its proprietary Encompass™ platform to create enhancement-targeting chimeric (ENTAC™) medicines. ENTACs harness the ability of DUBs to regulate proteins. By leveraging this natural cellular mechanism to enhance protein function, Entact is expanding the universe of treatable diseases.

We are seeking a leader with a strong background in compound management to join our growing team. The successful candidate will work closely with leadership and team members to help operationalize and maintain a compound management platform. They will be accountable for establishing and executing SOPs and processes related to storage of inventory, preparation of samples for testing, and shipping/receipt of supplies, samples, compounds for internal/external assays. This role will support compound management activities across multiple geographies, multiple departments and external CROs.

Responsibilities:

·    Lead all compound management functions including inventory of small molecules, biological materials, sample tracking, distribution, and data management

·    Work with external partners to establish compound archive and storage, distribution, and inventory management with a view to internalizing these capabilities as the company grows

·    Fulfill dry and solution-based compound sample requests for internal and external partners

·    Troubleshoot liquid handling platforms and analytical instrumentation

·    Maintain and improve sample workflows associated with storage, manual neat/weigh operations, liquid handling, and delivery of samples to internal and external teams.

·    Provide compound registration support

·    Develop tools to simplify internal processes and improve user experience

·    Manage processes associated with international and domestic shipments between collaborators and research sites, ensuring proper documentation is maintained

·    Test/Validate changes to software, hardware, and procedures. Proactively seek improvements to usability of these systems and production timelines

·    Create and maintain SOPs and job aids for critical processes

·    Troubleshoot software and hardware issues and resolve sample dispensing issues

·    Assist research team with day-to-day responsibilities, ensuring projects are supported in a timely, consistent manner

·    Establish processes for replenishment of consumables 

·    Continue customization of sample software, and work closely with vendors to solve problems

·    Maintain effective oral and written communication to research team members and provide support to ensure timelines are met

·    Provide additional support to the research Team as requested 

Who You Are:

·    Motivated, organized, detail oriented, and practical, with a growth mindset

·    Experienced in working with compound management CROs

·    Experienced in internalization of compound management for small molecules

·    Able to work both independently and within a multidisciplinary team

·    Proficient with LIMS integration, compound registration and inventory management software

·    Familiar with laboratory operations and management

·    Flexible and responsive to changing priorities

·    Enthusiastic for taking on new projects

·    Committed to maintaining the highest standards of safety and compliance

·    Experienced in shipping/receiving both domestically and internationally

Qualifications:

·    BS/MS or equivalent degree in chemical, biological, engineering sciences or related field with 5+ years working full time in a laboratory setting either in academia or industry

·    Excellent written, verbal, and interpersonal communication skills are required, with ability to work with/across a range of disciplines including biology, medicinal chemistry and bioassay

As a member of our diverse and growing team, you’ll help shape us into a company that takes its scientific mission seriously while providing a positive and supportive workplace environment and culture. With your insights, passion, and talent – we’ll bring novel therapeutics to the patients who need them the most.

We are an equal opportunity employer. We will not tolerate discrimination on the basis of race, color, national origin, sex, sexual orientation, gender identity, religion, age, disability, veteran's status, pregnancy, genetic information or on any basis prohibited by federal, state or local law.