Elayne Chan-Penebre, Ph.D., is Ph.D.-trained scientist with deep expertise in small molecule drug discovery and development across oncology, immunology, and neurodegeneration. As Senior Vice President of R&D at Dunad Therapeutics, she and the team advanced the company’s ALS program to Development Candidate nomination and beyond. Prior to Dunad, she led the Biology group at Faze Medicines, a biotechnology company focused on the discovery of therapies targeting biomolecular condensates across neurodegeneration and oncology indications. Earlier in her career she spent a decade at Epizyme where she delivered first-in-class development candidates for PRMT5 in oncology and advanced to IND for G9a in sickle cell disease. She participated in the ODAC for the FDA approval of Tazverik, an EZH2 inhibitor, in oncology. Elayne holds a Ph.D. in Molecular and Medical Genetics from the University of Toronto and completed her postdoctoral training at Boston Children's Hospital/Harvard Medical School under Dr. George Q. Daley.
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06/23/2026 Press Releases
Entact Bio Appoints John G. Houston, Ph.D., to its Board of Directors
A veteran biopharma innovator who helped advance the first FDA-approved PROTAC drug, Dr. Houston will strengthen Entact's leadership in induced proximity therapeutics. Houston's deep experience with protein degraders will be invaluable to supporting Entact’s development of ENTAC™ medicines, which leverage the same un...
02/08/2026 Publications
Targeted recruitment of USP15 enhances CTLA4 surface levels and restricts its degradation
09/17/2024 Press Releases
Entact Bio Appoints Ruben Tommasi, Ph.D., as Chief Scientific Officer
Veteran drug developer and R&D leader with three decades of pharmaceutical and biotech experience to oversee development of targeted protein enhancement modality Watertown, MA, September 17, 2024 – Entact Bio, a company committed to improving the lives of patients by developing precision medicines that enhance the fu...
05/29/2024 Press Releases
Entact Bio Appoints Michael Gutch, Ph.D., as Chief Operating Officer
Veteran pharma and biotech executive with 20 years of operations and finance experience joins world-leading team advancing novel targeted protein enhancement modality Watertown, MA, May 29, 2024 – Entact Bio, the pioneer of precision medicines that enhance the function of beneficial proteins, today announced the appo...